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Sustained inhibition of NPY/AgRP neuronal activity by FGF1

In rodent models of type 2 diabetes (T2D), central administration of FGF1 normalizes elevated blood glucose levels in a manner that is sustained for weeks or months. Increased activity of NPY/AgRP neurons in the hypothalamic arcuate nucleus (ARC) is implicated in the pathogenesis of hyperglycemia in...

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Detalles Bibliográficos
Autores principales:	Hwang, Eunsang, Scarlett, Jarrad M., Baquero, Arian F., Bennett, Camdin M., Dong, Yanbin, Chau, Dominic, Brown, Jenny M., Mercer, Aaron J., Meek, Thomas H., Grove, Kevin L., Phan, Bao Anh N., Morton, Gregory J., Williams, Kevin W., Schwartz, Michael W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536267/ https://www.ncbi.nlm.nih.gov/pubmed/35917179 http://dx.doi.org/10.1172/jci.insight.160891

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