Cargando…
CCR9 axis inhibition enhances hepatic migration of plasmacytoid DCs and protects against liver injury
Plasmacytoid dendritic cells (pDCs) perform dual proinflammatory and immunosuppressive roles. We recently reported the potential of pDC therapy for treatment of intractable acute liver failure. However, establishment of efficient methods to deliver pDCs to the liver is essential for future clinical...
Autores principales: | Koda, Yuzo, Nakamoto, Nobuhiro, Chu, Po-Sung, Teratani, Toshiaki, Ueno, Akihisa, Amiya, Takeru, Taniki, Nobuhito, Chiba, Sayako, Miyamoto, Kentaro, Sakamoto, Michiie, Kanai, Takanori |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536268/ https://www.ncbi.nlm.nih.gov/pubmed/35943802 http://dx.doi.org/10.1172/jci.insight.159910 |
Ejemplares similares
-
CD8(+) tissue-resident memory T cells promote liver fibrosis resolution by inducing apoptosis of hepatic stellate cells
por: Koda, Yuzo, et al.
Publicado: (2021) -
Bone marrow-derived macrophages distinct from tissue-resident macrophages play a pivotal role in Concanavalin A-induced murine liver injury via CCR9 axis
por: Amiya, Takeru, et al.
Publicado: (2016) -
IL-15-producing splenic B cells play pathogenic roles in the development of autoimmune hepatitis
por: Fujimori, Sota, et al.
Publicado: (2023) -
Hepatic Adenosine Triphosphate Reduction Through the Short‐Chain Fatty Acids–Peroxisome Proliferator‐Activated Receptor γ–Uncoupling Protein 2 Axis Alleviates Immune‐Mediated Acute Hepatitis in Inulin‐Supplemented Mice
por: Yamaguchi, Akihiro, et al.
Publicado: (2021) -
Myeloid TLR4 signaling promotes post-injury withdrawal resolution of murine liver fibrosis
por: Takimoto, Yoichi, et al.
Publicado: (2023)