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Succinate dehydrogenase inversely regulates red cell distribution width and healthy life span in chronically hypoxic mice

Increased red cell distribution width (RDW), which measures erythrocyte mean corpuscular volume (MCV) variability (anisocytosis), has been linked to early mortality in many diseases and in older adults through unknown mechanisms. Hypoxic stress has been proposed as a potential mechanism. However, ex...

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Detalles Bibliográficos
Autores principales: Baysal, Bora E., Alahmari, Abdulrahman A., Rodrick, Tori C., Tabaczynski, Debra, Curtin, Leslie, Seshadri, Mukund, Jones, Drew R., Sexton, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536274/
https://www.ncbi.nlm.nih.gov/pubmed/35881479
http://dx.doi.org/10.1172/jci.insight.158737