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Kinetic Characterization and Inhibition of Trypanosoma cruzi Hypoxanthine–Guanine Phosphoribosyltransferases

[Image: see text] Chagas disease, caused by the parasitic protozoan Trypanosoma cruzi, affects over 8 million people worldwide. Current antiparasitic treatments for Chagas disease are ineffective in treating advanced, chronic stages of the disease, and are noted for their toxicity. Like most parasit...

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Detalles Bibliográficos
Autores principales:	Glockzin, Kayla, Kostomiris, Demetrios, Minnow, Yacoba V. T., Suthagar, Kajitha, Clinch, Keith, Gai, Sinan, Buckler, Joshua N., Schramm, Vern L., Tyler, Peter C., Meek, Thomas D., Katzfuss, Ardala
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536471/ https://www.ncbi.nlm.nih.gov/pubmed/36193631 http://dx.doi.org/10.1021/acs.biochem.2c00312

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