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Sestrin2 Is Increased in Calcific Aortic Disease and Inhibits Osteoblastic Differentiation in Valvular Interstitial Cells via the Nuclear Factor E2–related Factor 2 Pathway
Sestrin2 (Sesn2) is involved in the progression of cardiovascular diseases, such as hypertension and myocardial infarction. This study aimed to examine Sesn2 expression in human calcific aortic valve disease (CAVD) and explore its possible mechanisms by which Sesn2 participates in this process. CAVD...
Autores principales: | Wang, Haixiong, Xi, Jicheng, Zhang, Zhibiao, Li, Jun, Guo, Liping, Li, Na, Sun, Yuehui, Li, Xiaofang, Han, Xuebin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Cardiovascular Pharmacology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536529/ https://www.ncbi.nlm.nih.gov/pubmed/35881902 http://dx.doi.org/10.1097/FJC.0000000000001314 |
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