A caspase–RhoGEF axis contributes to the cell size threshold for apoptotic death in developing Caenorhabditis elegans

A cell’s size affects the likelihood that it will die. But how is cell size controlled in this context and how does cell size impact commitment to the cell death fate? We present evidence that the caspase CED-3 interacts with the RhoGEF ECT-2 in Caenorhabditis elegans neuroblasts that generate “unwa...

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Detalles Bibliográficos
Autores principales: Sethi, Aditya, Wei, Hai, Mishra, Nikhil, Segos, Ioannis, Lambie, Eric J., Zanin, Esther, Conradt, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536578/
https://www.ncbi.nlm.nih.gov/pubmed/36201522
http://dx.doi.org/10.1371/journal.pbio.3001786

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