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Cross-GWAS coherence test at the gene and pathway level
Proximal genetic variants are frequently correlated, implying that the corresponding effect sizes detected by genome-wide association studies (GWAS) are also not independent. Methods already exist to account for this when aggregating effects from a single GWAS across genes or pathways. Here we prese...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536597/ https://www.ncbi.nlm.nih.gov/pubmed/36156592 http://dx.doi.org/10.1371/journal.pcbi.1010517 |