Cargando…
Prediction of odds for emergency cesarean section: A secondary analysis of the CHILD term birth cohort study
INTRODUCTION: Previously developed cesarean section (CS) and emergency CS prediction tools use antenatal and intrapartum risk factors. We aimed to develop a predictive model for the risk of emergency CS before the onset of labour utilizing antenatal obstetric and non-obstetric factors. METHODS: We c...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536615/ https://www.ncbi.nlm.nih.gov/pubmed/36201407 http://dx.doi.org/10.1371/journal.pone.0268229 |
_version_ | 1784803018799054848 |
---|---|
author | Tun, Mon H. Chari, Radha Kaul, Padma Mamede, Fabiana V. Paulden, Mike Lefebvre, Diana L. Turvey, Stuart E. Moraes, Theo J. Sears, Malcolm R. Subbarao, Padmaja Mandhane, Piush J. |
author_facet | Tun, Mon H. Chari, Radha Kaul, Padma Mamede, Fabiana V. Paulden, Mike Lefebvre, Diana L. Turvey, Stuart E. Moraes, Theo J. Sears, Malcolm R. Subbarao, Padmaja Mandhane, Piush J. |
author_sort | Tun, Mon H. |
collection | PubMed |
description | INTRODUCTION: Previously developed cesarean section (CS) and emergency CS prediction tools use antenatal and intrapartum risk factors. We aimed to develop a predictive model for the risk of emergency CS before the onset of labour utilizing antenatal obstetric and non-obstetric factors. METHODS: We completed a secondary analysis of data collected from the CHILD Cohort Study. The analysis was limited to term (≥37 weeks), singleton pregnant women with cephalic presentation. The sample was divided into a training and validation dataset. The emergency CS prediction model was developed in the training dataset and the performance accuracy was assessed by the area under the receiver operating characteristic curve(AUC) of the receiver operating characteristic analysis (ROC). Our final model was subsequently evaluated in the validation dataset. RESULTS: The participant sample consisted of 2,836 pregnant women. Mean age of participants was 32 years, mean BMI of 25.4 kg/m2 and 39% were nulliparous. 14% had emergency CS delivery. Each year of increasing maternal age increased the odds of emergency CS by 6% (adjusted Odds Ratio (aOR 1.06,1.02–1.08). Likewise, there was a 4% increase odds of emergency CS for each unit increase in BMI (aOR 1.04,1.02–1.06). In contrast, increase in maternal height has a negative association with emergency CS. The final emergency CS delivery predictive model included six variables (hypertensive disorders of pregnancy, antenatal depression, previous vaginal delivery, age, height, BMI). The AUC for our final prediction model was 0.74 (0.72–0.77) in the training set with a similar AUC in the validation dataset (0.77; 0.71–0.82). CONCLUSION: The developed and validated emergency CS delivery prediction model can be used in counselling prospective parents around their CS risk and healthcare resource planning. Further validation of the tool is suggested. |
format | Online Article Text |
id | pubmed-9536615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-95366152022-10-07 Prediction of odds for emergency cesarean section: A secondary analysis of the CHILD term birth cohort study Tun, Mon H. Chari, Radha Kaul, Padma Mamede, Fabiana V. Paulden, Mike Lefebvre, Diana L. Turvey, Stuart E. Moraes, Theo J. Sears, Malcolm R. Subbarao, Padmaja Mandhane, Piush J. PLoS One Research Article INTRODUCTION: Previously developed cesarean section (CS) and emergency CS prediction tools use antenatal and intrapartum risk factors. We aimed to develop a predictive model for the risk of emergency CS before the onset of labour utilizing antenatal obstetric and non-obstetric factors. METHODS: We completed a secondary analysis of data collected from the CHILD Cohort Study. The analysis was limited to term (≥37 weeks), singleton pregnant women with cephalic presentation. The sample was divided into a training and validation dataset. The emergency CS prediction model was developed in the training dataset and the performance accuracy was assessed by the area under the receiver operating characteristic curve(AUC) of the receiver operating characteristic analysis (ROC). Our final model was subsequently evaluated in the validation dataset. RESULTS: The participant sample consisted of 2,836 pregnant women. Mean age of participants was 32 years, mean BMI of 25.4 kg/m2 and 39% were nulliparous. 14% had emergency CS delivery. Each year of increasing maternal age increased the odds of emergency CS by 6% (adjusted Odds Ratio (aOR 1.06,1.02–1.08). Likewise, there was a 4% increase odds of emergency CS for each unit increase in BMI (aOR 1.04,1.02–1.06). In contrast, increase in maternal height has a negative association with emergency CS. The final emergency CS delivery predictive model included six variables (hypertensive disorders of pregnancy, antenatal depression, previous vaginal delivery, age, height, BMI). The AUC for our final prediction model was 0.74 (0.72–0.77) in the training set with a similar AUC in the validation dataset (0.77; 0.71–0.82). CONCLUSION: The developed and validated emergency CS delivery prediction model can be used in counselling prospective parents around their CS risk and healthcare resource planning. Further validation of the tool is suggested. Public Library of Science 2022-10-06 /pmc/articles/PMC9536615/ /pubmed/36201407 http://dx.doi.org/10.1371/journal.pone.0268229 Text en © 2022 Tun et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Tun, Mon H. Chari, Radha Kaul, Padma Mamede, Fabiana V. Paulden, Mike Lefebvre, Diana L. Turvey, Stuart E. Moraes, Theo J. Sears, Malcolm R. Subbarao, Padmaja Mandhane, Piush J. Prediction of odds for emergency cesarean section: A secondary analysis of the CHILD term birth cohort study |
title | Prediction of odds for emergency cesarean section: A secondary analysis of the CHILD term birth cohort study |
title_full | Prediction of odds for emergency cesarean section: A secondary analysis of the CHILD term birth cohort study |
title_fullStr | Prediction of odds for emergency cesarean section: A secondary analysis of the CHILD term birth cohort study |
title_full_unstemmed | Prediction of odds for emergency cesarean section: A secondary analysis of the CHILD term birth cohort study |
title_short | Prediction of odds for emergency cesarean section: A secondary analysis of the CHILD term birth cohort study |
title_sort | prediction of odds for emergency cesarean section: a secondary analysis of the child term birth cohort study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536615/ https://www.ncbi.nlm.nih.gov/pubmed/36201407 http://dx.doi.org/10.1371/journal.pone.0268229 |
work_keys_str_mv | AT tunmonh predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT chariradha predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT kaulpadma predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT mamedefabianav predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT pauldenmike predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT lefebvredianal predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT turveystuarte predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT moraestheoj predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT searsmalcolmr predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT subbaraopadmaja predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy AT mandhanepiushj predictionofoddsforemergencycesareansectionasecondaryanalysisofthechildtermbirthcohortstudy |