Cargando…

Therapeutic efficacy of rifalazil (KRM-1648) in a M. ulcerans-induced Buruli ulcer mouse model

Buruli ulcer (BU) is a skin disease caused by Mycobacterium ulcerans infection that requires long-term antibiotic treatment and/or surgical excision. In this study, we investigated the therapeutic efficacy of the rifamycin derivative, rifalazil (RLZ) (also known as KRM-1648), in an advanced M. ulcer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fukano, Hanako, Nakanaga, Kazue, Goto, Masamichi, Yoshida, Mitsunori, Ishii, Norihisa, Hoshino, Yoshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536621/ https://www.ncbi.nlm.nih.gov/pubmed/36201529 http://dx.doi.org/10.1371/journal.pone.0274742

Ejemplares similares

Complete Genome Sequence of Mycobacterium ulcerans subsp. shinshuense
por: Yoshida, Mitsunori, et al.
Publicado: (2016)

Naturally occurring a loss of a giant plasmid from Mycobacterium ulcerans subsp. shinshuense makes it non-pathogenic
por: Nakanaga, Kazue, et al.
Publicado: (2018)

Drugs for treating Buruli ulcer (Mycobacterium ulcerans disease)
por: Yotsu, Rie R, et al.
Publicado: (2018)

Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer
por: Suzuki, Toshihiko, et al.
Publicado: (2023)

On the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer
por: Doig, Kenneth D, et al.
Publicado: (2012)

The Incubation Period of Buruli Ulcer (Mycobacterium ulcerans Infection)
por: Trubiano, Jason A., et al.
Publicado: (2013)

Targeting the Mycobacterium ulcerans cytochrome bc(1):aa(3) for the treatment of Buruli ulcer
por: Scherr, Nicole, et al.
Publicado: (2018)

Spontaneous Clearance of Mycobacterium ulcerans in a Case of Buruli Ulcer
por: Gordon, Claire L., et al.
Publicado: (2011)

Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer
por: En, Junichiro, et al.
Publicado: (2017)

Human pathogenic Mycobacterium kansasii (former subtype I) with zoonotic potential isolated from a diseased indoor pet cat, Japan
por: Fukano, Hanako, et al.
Publicado: (2021)

Aquatic Insects and Mycobacterium ulcerans: An Association Relevant to Buruli Ulcer Control?
por: Silva, Manuel T, et al.
Publicado: (2007)

Risk of Buruli Ulcer and Detection of Mycobacterium ulcerans in Mosquitoes in Southeastern Australia
por: Lavender, Caroline J., et al.
Publicado: (2011)

Detection of Mycobacterium ulcerans in the Environment Predicts Prevalence of Buruli Ulcer in Benin
por: Williamson, Heather R., et al.
Publicado: (2012)

Linking the Mycobacterium ulcerans environment to Buruli ulcer disease: Progress and challenges
por: Dhungel, Laxmi, et al.
Publicado: (2021)

Complete Genome Sequence of Mycobacterium fortuitum subsp. fortuitum JCM 6387, a Type Strain of Human-Pathogenic Mycobacteria Showing Inducible Macrolide Resistance
por: Yoshida, Mitsunori, et al.
Publicado: (2022)

Impact of Mycobacterium ulcerans Biofilm on Transmissibility to Ecological Niches and Buruli Ulcer Pathogenesis
por: Marsollier, Laurent, et al.
Publicado: (2007)

Mycobacterium ulcerans in Mosquitoes Captured during Outbreak of Buruli Ulcer, Southeastern Australia
por: Johnson, Paul D.R., et al.
Publicado: (2007)

Mycobacterium ulcerans Persistence at a Village Water Source of Buruli Ulcer Patients
por: Bratschi, Martin W., et al.
Publicado: (2014)

A protocol for culturing environmental strains of the Buruli ulcer agent, Mycobacterium ulcerans
por: Zingue, Dezemon, et al.
Publicado: (2018)

Seasonal Pattern of Mycobacterium ulcerans, the Causative Agent of Buruli Ulcer, in the Environment in Ghana
por: Aboagye, Samuel Yaw, et al.
Publicado: (2017)

Spatial Distribution of Mycobacterium ulcerans in Buruli Ulcer Lesions: Implications for Laboratory Diagnosis
por: Ruf, Marie-Thérèse, et al.
Publicado: (2016)

Understanding the transmission of Mycobacterium ulcerans: A step towards controlling Buruli ulcer
por: Muleta, Anthony J., et al.
Publicado: (2021)

Repurposing of statins for Buruli Ulcer treatment: antimicrobial activity against Mycobacterium ulcerans
por: Dominguez, Juan, et al.
Publicado: (2023)

A Case of Mycobacterial Skin Disease Caused by Mycobacterium peregrinum, and a Review of Cutaneous Infection
por: Kamijo, Fuminao, et al.
Publicado: (2012)

Distribution of Mycobacterium ulcerans in Buruli Ulcer Endemic and Non-Endemic Aquatic Sites in Ghana
por: Williamson, Heather R., et al.
Publicado: (2008)

Buruli Ulcer (M. ulcerans Infection): New Insights, New Hope for Disease Control
por: Johnson, Paul D. R, et al.
Publicado: (2005)

Serologic response to culture filtrate antigens of Mycobacterium ulcerans during Buruli ulcer disease.
por: Dobos, K M, et al.
Publicado: (2000)

Mycobacterium ulcerans Disease (Buruli Ulcer) in Rural Hospital, Southern Benin, 1997–2001
por: Debacker, Martine, et al.
Publicado: (2004)

Fish and amphibians as potential reservoirs of Mycobacterium ulcerans, the causative agent of Buruli ulcer disease
por: Willson, Sarah J., et al.
Publicado: (2013)

Environmental transmission of Mycobacterium ulcerans drives dynamics of Buruli ulcer in endemic regions of Cameroon
por: Garchitorena, Andrés, et al.
Publicado: (2015)

Mycobacterium ulcerans Population Genomics To Inform on the Spread of Buruli Ulcer across Central Africa
por: Vandelannoote, Koen, et al.
Publicado: (2019)

Decrease in Mycobacterium ulcerans disease (Buruli ulcer) in the Lalo District of Bénin (West Africa)
por: Anagonou, Esaï Gimatal, et al.
Publicado: (2019)

Evidences of the Low Implication of Mosquitoes in the Transmission of Mycobacterium ulcerans, the Causative Agent of Buruli Ulcer
por: Djouaka, Rousseau, et al.
Publicado: (2017)

PPE Barcoding Identifies Biclonal Mycobacterium ulcerans Buruli Ulcer, Côte d’Ivoire
por: Tchan, B. G. O., et al.
Publicado: (2023)

The compound TB47 is highly bactericidal against Mycobacterium ulcerans in a Buruli ulcer mouse model
por: Liu, Yang, et al.
Publicado: (2019)

Complete Genome Sequence of Mycobacterium xenopi JCM15661(T), Obtained Using Nanopore and Illumina Sequencing Technologies
por: Yoshida, Mitsunori, et al.
Publicado: (2020)

Complete Genome Sequence of Mycobacterium heckeshornense JCM 15655(T), Closely Related to a Pathogenic Nontuberculous Mycobacterial Species, Mycobacterium xenopi
por: Yoshida, Mitsunori, et al.
Publicado: (2021)

Correction: Buruli Ulcer (M. ulcerans Infection): New Insights, New Hope for Disease Control
por: Johnson, Paul D. R, et al.
Publicado: (2005)

Locally Confined Clonal Complexes of Mycobacterium ulcerans in Two Buruli Ulcer Endemic Regions of Cameroon
por: Bolz, Miriam, et al.
Publicado: (2015)

Recent advances: role of mycolactone in the pathogenesis and monitoring of Mycobacterium ulcerans infection/Buruli ulcer disease
por: Sarfo, Fred Stephen, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_pfsk3rap90mskpfdnn1003nbcg