A Deep Survival EWAS approach estimating risk profile based on pre-diagnostic DNA methylation: An application to breast cancer time to diagnosis

Previous studies for cancer biomarker discovery based on pre-diagnostic blood DNA methylation (DNAm) profiles, either ignore the explicit modeling of the Time To Diagnosis (TTD), or provide inconsistent results. This lack of consistency is likely due to the limitations of standard EWAS approaches, t...

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Detalles Bibliográficos
Autores principales: Massi, Michela Carlotta, Dominoni, Lorenzo, Ieva, Francesca, Fiorito, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536632/
https://www.ncbi.nlm.nih.gov/pubmed/36155971
http://dx.doi.org/10.1371/journal.pcbi.1009959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536632/
https://www.ncbi.nlm.nih.gov/pubmed/36155971
http://dx.doi.org/10.1371/journal.pcbi.1009959

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