Cargando…

A Deep Survival EWAS approach estimating risk profile based on pre-diagnostic DNA methylation: An application to breast cancer time to diagnosis

Previous studies for cancer biomarker discovery based on pre-diagnostic blood DNA methylation (DNAm) profiles, either ignore the explicit modeling of the Time To Diagnosis (TTD), or provide inconsistent results. This lack of consistency is likely due to the limitations of standard EWAS approaches, t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Massi, Michela Carlotta, Dominoni, Lorenzo, Ieva, Francesca, Fiorito, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536632/ https://www.ncbi.nlm.nih.gov/pubmed/36155971 http://dx.doi.org/10.1371/journal.pcbi.1009959

Ejemplares similares

pwrEWAS: a user-friendly tool for comprehensive power estimation for epigenome wide association studies (EWAS)
por: Graw, Stefan, et al.
Publicado: (2019)

An interview with Ewa Czochrowska
por: Czochrowska, Ewa
Publicado: (2018)

Ten Years of EWAS
por: Wei, Siyu, et al.
Publicado: (2021)

DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures
por: Gomez-Alonso, Monica del C., et al.
Publicado: (2021)

Data mining application to healthcare fraud detection: a two-step unsupervised clustering method for outlier detection with administrative databases
por: Massi, Michela Carlotta, et al.
Publicado: (2020)

EWAS Data Hub: a resource of DNA methylation array data and metadata
por: Xiong, Zhuang, et al.
Publicado: (2020)

Epigenome-Wide Association Studies (EWAS) in Cancer
por: Verma, Mukesh
Publicado: (2012)

Diversity in EWAS: current state, challenges, and solutions
por: Breeze, Charles E., et al.
Publicado: (2022)

Ewa Orłowska on relational methods in logic and computer science
por: Golińska-Pilarek, Joanna, et al.
Publicado: (2018)

Choice of surrogate tissue influences neonatal EWAS findings
por: Lin, Xinyi, et al.
Publicado: (2017)

Dual adversarial deconfounding autoencoder for joint batch-effects removal from multi-center and multi-scanner radiomics data
por: Cavinato, Lara, et al.
Publicado: (2023)

Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study
por: Braun, Kim V. E., et al.
Publicado: (2017)

EWAS: epigenome-wide association study software 2.0
por: Xu, Jing, et al.
Publicado: (2018)

The EWAS Catalog: a database of epigenome-wide association studies
por: Battram, Thomas, et al.
Publicado: (2022)

Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation
por: Islam, Sumaiya A., et al.
Publicado: (2019)

An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus
por: Patel, Chirag J., et al.
Publicado: (2010)

EWAS Atlas: a curated knowledgebase of epigenome-wide association studies
por: Li, Mengwei, et al.
Publicado: (2019)

The EpiDiverse Plant Epigenome-Wide Association Studies (EWAS) Pipeline
por: Can, Sultan Nilay, et al.
Publicado: (2021)

EWAS: epigenome-wide association studies software 1.0 – identifying the association between combinations of methylation levels and diseases
por: Xu, Jing, et al.
Publicado: (2016)

Incidence and predictors of excessive warfarin anticoagulation in patients with atrial fibrillation—The EWA study
por: Jaakkola, Samuli, et al.
Publicado: (2017)

Diabetic Retinopathy Environment-Wide Association Study (EWAS) in NHANES 2005–2008
por: Blighe, Kevin, et al.
Publicado: (2020)

CLARITE Facilitates the Quality Control and Analysis Process for EWAS of Metabolic-Related Traits
por: Lucas, Anastasia M., et al.
Publicado: (2019)

A comparison of the genes and genesets identified by GWAS and EWAS of fifteen complex traits
por: Battram, Thomas, et al.
Publicado: (2022)

A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes
por: You, Chenglong, et al.
Publicado: (2020)

Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals
por: Chen, Yuqing, et al.
Publicado: (2021)

EWAS Open Platform: integrated data, knowledge and toolkit for epigenome-wide association study
por: Xiong, Zhuang, et al.
Publicado: (2021)

EWAS of Monozygotic Twins Implicate a Role of mTOR Pathway in Pathogenesis of Tic Spectrum Disorder
por: Hildonen, Mathis, et al.
Publicado: (2021)

Ergonomic workplace analysis (EWA) as a model for creating an instrument to assess rest locations for truck drivers
por: Rocha, Felipe Pereira, et al.
Publicado: (2023)

Epigenome-Wide Association Study (EWAS) of Blood Lipids in Healthy Population from STANISLAS Family Study (SFS)
por: Xie, Ting, et al.
Publicado: (2019)

EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection
por: Lee, Yunsung, et al.
Publicado: (2022)

Epigenome-wide association study (EWAS) for potential transgenerational disease epigenetic biomarkers in sperm following ancestral exposure to the pesticide methoxychlor
por: Nilsson, Eric E, et al.
Publicado: (2020)

Identification of NHLRC1 as a Novel AKT Activator from a Lung Cancer Epigenome-Wide Association Study (EWAS)
por: Faltus, Christian, et al.
Publicado: (2022)

Early Treatment for Women with Alcohol Addiction (EWA) Reduces Mortality: A Randomized Controlled Trial with Long-Term Register Follow-up
por: Gjestad, Rolf, et al.
Publicado: (2011)

Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis
por: Feng, Xiaoshuang, et al.
Publicado: (2023)

Using estimated probability of pre-diagnosis behavior as a predictor of cancer survival time: an example in esophageal cancer
por: Fahey, Paul P., et al.
Publicado: (2020)

Estimation of the methylation pattern distribution from deep sequencing data
por: Lin, Peijie, et al.
Publicado: (2015)

Pre-diagnosis diet and survival after a diagnosis of ovarian cancer
por: Playdon, Mary C, et al.
Publicado: (2017)

Use of deep learning in the MRI diagnosis of Chiari malformation type I
por: Tanaka, Kaishin W., et al.
Publicado: (2022)

Comment on Małgorzata Krówczyńska and Ewa Wilk. Environmental and Occupational Exposure to Asbestos as a Result of Consumption and Use in Poland. Int. J. Environ. Res. Public Health 2019, 16, 2611
por: Świątkowska, Beata, et al.
Publicado: (2020)

Notch, SUMOylation, and ESR-Mediated Signalling Are the Main Molecular Pathways Showing Significantly Different Epimutation Scores between Expressing or Not Oestrogen Receptor Breast Cancer in Three Public EWAS Datasets
por: Corsaro, Luigi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_srgvdk0ejtaanomb56d85skbe2