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Transcriptional changes in Plasmodium falciparum upon conditional knock down of mitochondrial ribosomal proteins RSM22 and L23

The mitochondrion of malaria parasites is an attractive antimalarial drug target, which require mitoribosomes to translate genes encoded in the mitochondrial (mt) DNA. Plasmodium mitoribosomes are composed of highly fragmented ribosomal RNA (rRNA) encoded in the mtDNA. All mitoribosomal proteins (MR...

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Detalles Bibliográficos
Autores principales: Dass, Swati, Mather, Michael W., Morrisey, Joanne M., Ling, Liqin, Vaidya, Akhil B., Ke, Hangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536634/
https://www.ncbi.nlm.nih.gov/pubmed/36201550
http://dx.doi.org/10.1371/journal.pone.0274993