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Mouse models of COVID-19 recapitulate inflammatory pathways rather than gene expression

How well mouse models recapitulate the transcriptional profiles seen in humans remains debatable, with both conservation and diversity identified in various settings. Herein we use RNA-Seq data and bioinformatics approaches to analyze the transcriptional responses in SARS-CoV-2 infected lungs, compa...

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Detalles Bibliográficos
Autores principales:	Bishop, Cameron R., Dumenil, Troy, Rawle, Daniel J., Le, Thuy T., Yan, Kexin, Tang, Bing, Hartel, Gunter, Suhrbier, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536645/ https://www.ncbi.nlm.nih.gov/pubmed/36155667 http://dx.doi.org/10.1371/journal.ppat.1010867

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