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Evolution of SIVmac239 following serial passaging in humanized mice

Serial passage of SIVmac239 allows for greater understanding of the genetic changes necessary for cross‐species transmission of primate lentiviruses into humans. Using humanized mice, we show that adaptive mutations continue to accumulate in SIVmac239 during four serial passages, with persistent CD4...

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Detalles Bibliográficos
Autores principales: Curlin, James Z., Schmitt, Kimberly, Remling‐Mulder, Leila, Morrison, Jared, Baczenas, John J., Tibbits, Corina Valencia, Goff, Kelly, O'Connor, Shelby, Stenglein, Mark, Marx, Preston, Akkina, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536747/
https://www.ncbi.nlm.nih.gov/pubmed/36030392
http://dx.doi.org/10.1111/jmp.12614