Egg-adaptive mutations of human influenza H3N2 virus are contingent on natural evolution

Egg-adaptive mutations in influenza hemagglutinin (HA) often emerge during the production of egg-based seasonal influenza vaccines, which contribute to the largest share in the global influenza vaccine market. While some egg-adaptive mutations have minimal impact on the HA antigenicity (e.g. G186V),...

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Detalles Bibliográficos
Autores principales: Liang, Weiwen, Tan, Timothy J. C., Wang, Yiquan, Lv, Huibin, Sun, Yuanxin, Bruzzone, Roberto, Mok, Chris K. P., Wu, Nicholas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536752/
https://www.ncbi.nlm.nih.gov/pubmed/36155668
http://dx.doi.org/10.1371/journal.ppat.1010875

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