Independent regulation of mitochondrial DNA quantity and quality in Caenorhabditis elegans primordial germ cells

Mitochondria harbor an independent genome, called mitochondrial DNA (mtDNA), which contains essential metabolic genes. Although mtDNA mutations occur at high frequency, they are inherited infrequently, indicating that germline mechanisms limit their accumulation. To determine how germline mtDNA is r...

Descripción completa

Detalles Bibliográficos
Autores principales: Schwartz, Aaron ZA, Tsyba, Nikita, Abdu, Yusuff, Patel, Maulik R, Nance, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536838/
https://www.ncbi.nlm.nih.gov/pubmed/36200990
http://dx.doi.org/10.7554/eLife.80396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536838/
https://www.ncbi.nlm.nih.gov/pubmed/36200990
http://dx.doi.org/10.7554/eLife.80396

Ejemplares similares