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Independent regulation of mitochondrial DNA quantity and quality in Caenorhabditis elegans primordial germ cells
Mitochondria harbor an independent genome, called mitochondrial DNA (mtDNA), which contains essential metabolic genes. Although mtDNA mutations occur at high frequency, they are inherited infrequently, indicating that germline mechanisms limit their accumulation. To determine how germline mtDNA is r...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536838/ https://www.ncbi.nlm.nih.gov/pubmed/36200990 http://dx.doi.org/10.7554/eLife.80396 |