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High Glucose Promotes Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance and Invasion through Modulating ROS/MMP-3 Signaling Pathway

Pancreatic ductal adenocarcinoma (PDA) is often concomitant with diabetes mellitus, which mainly manifests as an increased blood glucose level. Previous studies revealed that diabetic status reduced the survival and blunted gemcitabine sensitivity in PDA patients. This study is aimed at analyzing th...

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Detalles Bibliográficos
Autores principales:	Deng, Junyuan, Guo, Yujie, Hu, Xiaomu, Du, Jiali, Gu, Jichun, Kong, Lei, Tao, Baian, Fu, Deliang, Ying, Tianlei, Li, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536998/ https://www.ncbi.nlm.nih.gov/pubmed/36211828 http://dx.doi.org/10.1155/2022/3243647

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