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Downregulation of SIRT3 Aggravates Lung Ischemia Reperfusion Injury by Increasing Mitochondrial Fission and Oxidative Stress through HIF-1α-Dependent Mechanisms

Lung ischemia-reperfusion injury (LIRI) is a severe multifaceted pathological condition that can lead to poor patient outcome where oxidative stress and the resulting inflammatory response can trigger and exacerbate tissue damage in LIRI patients. Sirtuin3 (SIRT3), a member of the sirtuin family, pr...

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Detalles Bibliográficos
Autores principales:	Liu, Chunxia, Pei, Shenglin, Dai, Huijun, Liu, Zhen, Ye, Mengling, Liu, Hao, He, Xiaojing, Wu, Siyi, Qin, Yi, Lin, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537006/ https://www.ncbi.nlm.nih.gov/pubmed/36211825 http://dx.doi.org/10.1155/2022/9041914

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