Cargando…

Downregulated PRNP Facilitates Cell Proliferation and Invasion and Has Effect on the Immune Regulation in Ovarian Cancer

BACKGROUND: Ovarian cancer (OC) seriously threatens women's life. Ferroptosis plays an essential role in the initiation and development of OC. However, more molecular targets and mechanisms for ferroptosis in OC remain to be further elucidated. METHODS: Several OC datasets were integrated in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Kuan, Zhang, Xiaofang, Zhou, Lei, Li, Juanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537007/ https://www.ncbi.nlm.nih.gov/pubmed/36213323 http://dx.doi.org/10.1155/2022/3205040

Ejemplares similares

Downregulated ferroptosis‐related gene SQLE facilitates temozolomide chemoresistance, and invasion and affects immune regulation in glioblastoma
por: Yao, Lei, et al.
Publicado: (2022)

Downregulated ADARB1 Facilitates Cell Proliferation, Invasion and has Effect on the Immune Regulation in Ovarian Cancer
por: Zhu, Wei, et al.
Publicado: (2021)

The bioinformatics and experimental analysis of the novel roles of virus infection-associated gene CDC20 for prognosis and immune infiltration in hepatocellular carcinoma
por: Li, Juanni, et al.
Publicado: (2022)

Copper homeostasis-associated gene PRNP regulates ferroptosis and immune infiltration in breast cancer
por: Lin, Changwei, et al.
Publicado: (2023)

Prognostic Value and Therapeutic Potential of CBX Family Members in Ovarian Cancer
por: Hu, Kuan, et al.
Publicado: (2022)

An integrative pan cancer analysis of RET aberrations and their potential clinical implications
por: Zhou, Lei, et al.
Publicado: (2022)

Spectrum of BRCA1 interacting helicase 1 aberrations and potential prognostic and therapeutic implication: a pan cancer analysis
por: Long, Guo, et al.
Publicado: (2023)

The downregulation of LINC00273 inhibits the proliferation, invasion, and migration of ovarian cancer cells in vivo and in vitro
por: Shu, Chenggan, et al.
Publicado: (2022)

Comprehensive Analysis of YTH Domain Family in Lung Adenocarcinoma: Expression Profile, Association with Prognostic Value, and Immune Infiltration
por: Hu, Kuan, et al.
Publicado: (2021)

Integrated analysis of expression, prognostic value and immune infiltration of GSDMs in hepatocellular carcinoma
por: Hu, Kuan, et al.
Publicado: (2021)

Prion Protein PRNP: A New Player in Innate Immunity? The Aβ Connection
por: Lathe, Richard, et al.
Publicado: (2017)

Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β-catenin signaling pathway
por: Yi, Yun, et al.
Publicado: (2021)

Mutational analysis of PRNP in Alzheimer’s disease and frontotemporal dementia in China
por: Zhang, Weiwei, et al.
Publicado: (2016)

Polymorphism of prion protein gene (PRNP) in Nigerian sheep
por: Adeola, Adeniyi C., et al.
Publicado: (2023)

Hotair promotes the migration and proliferation in ovarian cancer by miR-222-3p/CDK19 axis
por: Fan, Lili, et al.
Publicado: (2022)

MiR-455-3p downregulation facilitates cell proliferation and invasion and predicts poor prognosis of osteosarcoma
por: Yi, Xijun, et al.
Publicado: (2020)

Prognostic Value of PLXND1 and TGF-β1 Coexpression and Its Correlation With Immune Infiltrates in Hepatocellular Carcinoma
por: Li, Juanni, et al.
Publicado: (2021)

ALKBH family members as novel biomarkers and prognostic factors in human breast cancer
por: Chen, Hongxi, et al.
Publicado: (2022)

Downregulation of hTERT contributes to ovarian cancer apoptosis and inhibits proliferation of ovarian cancer cells
por: Wang, Qing-An-Zi, et al.
Publicado: (2020)

SDHB downregulation facilitates the proliferation and invasion of colorectal cancer through AMPK functions excluding those involved in the modulation of aerobic glycolysis
por: Xiao, Zhiming, et al.
Publicado: (2018)

Novel mutation of the PRNP gene of a clinical CJD case
por: Kotta, Konstantia, et al.
Publicado: (2006)

A nonsense mutation in PRNP associated with clinical Alzheimer's disease()
por: Guerreiro, Rita, et al.
Publicado: (2014)

Review on PRNP genetics and susceptibility to chronic wasting disease of Cervidae
por: Moazami-Goudarzi, Katayoun, et al.
Publicado: (2021)

Diverse Chromobox Family Members: Potential Prognostic Biomarkers and Therapeutic Targets in Head and Neck Squamous Cell Carcinoma
por: Hu, Kuan, et al.
Publicado: (2022)

IGF-1-Induced Enhancement of PRNP Expression Depends on the Negative Regulation of Transcription Factor FOXO3a
por: Liu, Ting, et al.
Publicado: (2013)

Overexpression of TROP2 promotes proliferation and invasion of ovarian cancer cells
por: Wu, Bin, et al.
Publicado: (2017)

The novel roles of virus infection-associated gene CDKN1A in chemoresistance and immune infiltration of glioblastoma
por: Hu, Kuan, et al.
Publicado: (2021)

MicroRNA-505 is downregulated in human osteosarcoma and regulates cell proliferation, migration and invasion
por: Liu, Yu-Jiang, et al.
Publicado: (2018)

RECQL4, Negatively Regulated by miR-10a-5p, Facilitates Cell Proliferation and Invasion via MAFB in Ovarian Cancer
por: Guo, Li, et al.
Publicado: (2020)

High Expression of PRNP Predicts Poor Prognosis in Korean Patients with Gastric Cancer
por: Choi, Minseok, et al.
Publicado: (2022)

Expression profile and prognostic values of Chromobox family members in human glioblastoma
por: Li, Juanni, et al.
Publicado: (2022)

Suramin inhibits cell proliferation in ovarian and cervical cancer by downregulating heparanase expression
por: Li, HuaPing, et al.
Publicado: (2015)

MicroRNA miR-145-5p inhibits Phospholipase D 5 (PLD5) to downregulate cell proliferation and metastasis to mitigate prostate cancer
por: liu, Juanni, et al.
Publicado: (2021)

SPARC Is a Key Regulator of Proliferation, Apoptosis and Invasion in Human Ovarian Cancer
por: Chen, Jie, et al.
Publicado: (2012)

Vitamin D and DDX4 regulate the proliferation and invasion of ovarian cancer cells
por: Chen, Youguo, et al.
Publicado: (2018)

Upregulation of MiR-205 transcriptionally suppresses SMAD4 and PTEN and contributes to human ovarian cancer progression
por: Li, Juanni, et al.
Publicado: (2017)

Evidence for a Pathogenic Role of Different Mutations at Codon 188 of PRNP
por: Roeber, Sigrun, et al.
Publicado: (2008)

PRNP promoter polymorphisms are associated with BSE susceptibility in Swiss and German cattle
por: Haase, Bianca, et al.
Publicado: (2007)

Knockdown of the bovine prion gene PRNP by RNA interference (RNAi) technology
por: Sutou, Shizuyo, et al.
Publicado: (2007)

A robust, low- to medium-throughput prnp genotyping system in sheep
por: Buitkamp, Johannes, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_vqeq2sribli6j5t00rml2o53pf