Conformational change of organic cofactor PLP is essential for catalysis in PLP-dependent enzymes

Pyridoxal 5’-phosphate (PLP)-dependent enzymes are ubiquitous, catalyzing various biochemical reactions of approximately 4% of all classified enzymatic activities. They transform amines and amino acids into important metabolites or signaling molecules and are important drug targets in many diseases....

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Detalles Bibliográficos
Autores principales: Ngo, Ho-Phuong-Thuy, Nguyen, Diem Quynh, Park, Hyunjae, Park, Yoon Sik, Kwak, Kiwoong, Kim, Taejoon, Lee, Jang Ho, Cho, Kyoung Sang, Kang, Lin-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Contributed Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537024/
https://www.ncbi.nlm.nih.gov/pubmed/36104257
http://dx.doi.org/10.5483/BMBRep.2022.55.9.090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537024/
https://www.ncbi.nlm.nih.gov/pubmed/36104257
http://dx.doi.org/10.5483/BMBRep.2022.55.9.090

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