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Conformational change of organic cofactor PLP is essential for catalysis in PLP-dependent enzymes
Pyridoxal 5’-phosphate (PLP)-dependent enzymes are ubiquitous, catalyzing various biochemical reactions of approximately 4% of all classified enzymatic activities. They transform amines and amino acids into important metabolites or signaling molecules and are important drug targets in many diseases....
Autores principales: | Ngo, Ho-Phuong-Thuy, Nguyen, Diem Quynh, Park, Hyunjae, Park, Yoon Sik, Kwak, Kiwoong, Kim, Taejoon, Lee, Jang Ho, Cho, Kyoung Sang, Kang, Lin-Woo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537024/ https://www.ncbi.nlm.nih.gov/pubmed/36104257 http://dx.doi.org/10.5483/BMBRep.2022.55.9.090 |
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