Deciphering transcriptome alterations in bone marrow hematopoiesis at single-cell resolution in immune thrombocytopenia

Immune thrombocytopenia (ITP) is an autoimmune disorder, in which megakaryocyte dysfunction caused by an autoimmune reaction can lead to thrombocytopenia, although the underlying mechanisms remain unclear. Here, we performed single-cell transcriptome profiling of bone marrow CD34(+) hematopoietic st...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Zuo, Xinyi, Chen, Peng, Hu, Xiang, Sheng, Zi, Liu, Anli, Liu, Qiang, Leng, Shaoqiu, Zhang, Xiaoyu, Li, Xin, Wang, Limei, Feng, Qi, Li, Chaoyang, Hou, Ming, Chu, Chong, Ma, Shihui, Wang, Shuwen, Peng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537316/
https://www.ncbi.nlm.nih.gov/pubmed/36202780
http://dx.doi.org/10.1038/s41392-022-01167-9

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