Ameliorative effect of Lactobacillus rhamnosus GG on acetaminophen-induced hepatotoxicity via PKC/Nrf2/PGC-1α pathway

BACKGROUND: Acetaminophen (APAP) overdose is a common cause of hepatotoxicity. Antioxidants like N-acetyl cysteine are recommended as a therapeutic option; nevertheless, it has limitations. The search for efficient alternatives is ongoing. Probiotics are live microorganisms that maintain a healthy g...

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Detalles Bibliográficos
Autores principales: Ahmed, Hend M., Shehata, Hanan H., El-Saeed, Gamila S. M., Gabal, Hoda H. Abou, El-Daly, Sherien M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537380/
https://www.ncbi.nlm.nih.gov/pubmed/36201094
http://dx.doi.org/10.1186/s43141-022-00422-4

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