Targeting the innate repair receptor axis via erythropoietin or pyroglutamate helix B surface peptide attenuates hemolytic-uremic syndrome in mice

Hemolytic-uremic syndrome (HUS) can occur as a systemic complication of infections with Shiga toxin (Stx)-producing Escherichia coli and is characterized by microangiopathic hemolytic anemia and acute kidney injury. Hitherto, therapy has been limited to organ-supportive strategies. Erythropoietin (E...

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Detalles Bibliográficos
Autores principales: Dennhardt, Sophie, Pirschel, Wiebke, Wissuwa, Bianka, Imhof, Diana, Daniel, Christoph, Kielstein, Jan T., Hennig-Pauka, Isabel, Amann, Kerstin, Gunzer, Florian, Coldewey, Sina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537456/
https://www.ncbi.nlm.nih.gov/pubmed/36211426
http://dx.doi.org/10.3389/fimmu.2022.1010882

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