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Regulation of serine palmitoyl-transferase and Rac1–Nox2 signaling in diabetic retinopathy
Hyperlipidemia is considered as one of the major systemic factors associated with the development of diabetic retinopathy, and animal models have documented that its presence in a hyperglycemic environment exacerbates cytosolic ROS production (via activation of the Rac1–Nox2 axis) and mitochondrial...
Autores principales: | Alka, Kumari, Mohammad, Ghulam, Kowluru, Renu A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537524/ https://www.ncbi.nlm.nih.gov/pubmed/36202842 http://dx.doi.org/10.1038/s41598-022-20243-2 |
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