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Elucidation of the binding mechanism of astragaloside IV derivative with human serum albumin and its cardiotoxicity in zebrafish embryos

LS-102 is a new derivative of astragaloside IV (AGS IV) that has been shown to possess potentially significant cardioprotective effects. However, there are no reports concerning its interaction with human serum albumin (HSA) and toxicology in vertebrates. The present investigation was undertaken to...

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Detalles Bibliográficos
Autores principales:	Wu, You-Jiao, Li, Zhan-Hua, Li, Jiu-Yan, Zhou, Yan, Wang, Run-Yue, Chen, Xiao-Yi, Qing, Lin-Sen, Luo, Pei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537572/ https://www.ncbi.nlm.nih.gov/pubmed/36210826 http://dx.doi.org/10.3389/fphar.2022.987882

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