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Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection

Cellular proteins CPSF6, NUP153 and SEC24C play crucial roles in HIV-1 infection. While weak interactions of short phenylalanine-glycine (FG) containing peptides with isolated capsid hexamers have been characterized, how these cellular factors functionally engage with biologically relevant mature HI...

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Detalles Bibliográficos
Autores principales: Wei, Guochao, Iqbal, Naseer, Courouble, Valentine V., Francis, Ashwanth C., Singh, Parmit K., Hudait, Arpa, Annamalai, Arun S., Bester, Stephanie, Huang, Szu-Wei, Shkriabai, Nikoloz, Briganti, Lorenzo, Haney, Reed, KewalRamani, Vineet N., Voth, Gregory A., Engelman, Alan N., Melikyan, Gregory B., Griffin, Patrick R., Asturias, Francisco, Kvaratskhelia, Mamuka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537594/
https://www.ncbi.nlm.nih.gov/pubmed/36202818
http://dx.doi.org/10.1038/s41467-022-33662-6

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