Use of Immune Checkpoint Inhibitors in Elderly Patients With Chronic Kidney Disease and Renal Cell Carcinoma Metastasis of the Parotid Gland: Case Report and Review of the Literature

Renal cell carcinoma metastasis of the parotid gland is extremely rare, and the present literature review found only 23 cases reported in the last two decades. We present a case of a 75-year-old woman with a colon cancer history who had parotid gland metastasis as the first manifestation of second p...

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Detalles Bibliográficos
Autores principales: Parosanu, Andreea, Orlov Slavu, Cristina, Pirlog, Cristina, Stanciu, Ioana M, Nitipir, Cornelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
General Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537597/
https://www.ncbi.nlm.nih.gov/pubmed/36225438
http://dx.doi.org/10.7759/cureus.28868
Descripción
Sumario:Renal cell carcinoma metastasis of the parotid gland is extremely rare, and the present literature review found only 23 cases reported in the last two decades. We present a case of a 75-year-old woman with a colon cancer history who had parotid gland metastasis as the first manifestation of second primary kidney cancer. The presence of multiple comorbidities affected medical decision-making. Therefore the patient was treated primarily with immunotherapy. After four cycles of dual immune checkpoint blockade, this advanced patient still benefited and was changed to nivolumab monotherapy as maintenance therapy.

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