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4-(2-Butyl-6,7-dichloro-2-cyclopentyl-indan-1-on-5-yl) oxobutyric acid inhibits angiogenesis via modulation of vascular endothelial growth factor receptor 2 signaling pathway

4-(2-Butyl-6,7-dichloro-2-cyclopentyl-indan-1-on-5-yl) oxobutyric acid (DCPIB), was discovered to be a potent and specific antagonist of volume-regulated anion channel that is closely linked to angiogenesis. However, the effect of DCPIB on angiogenesis remains unclear. Here, we found that DCPIB inhi...

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Detalles Bibliográficos
Autores principales: Zhou, Tianli, Li, Yunda, Zhang, Heqiang, Pan, Lei, Pang, Jinglong, Yuan, Qian, Li, Guiyang, Jie, Lingjun, Wang, Yan, Zhang, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537693/
https://www.ncbi.nlm.nih.gov/pubmed/36211567
http://dx.doi.org/10.3389/fcvm.2022.969616