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Behavioral responses to risk promote vaccinating high‐contact individuals first

How should communities prioritize COVID‐19 vaccinations? Prior studies found that prioritizing the elderly and most vulnerable minimizes deaths. However, prior research has ignored how behavioral responses to risk of disease endogenously change transmission rates. We show that incorporating risk‐dri...

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Autor principal: Rahmandad, Hazhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537883/
https://www.ncbi.nlm.nih.gov/pubmed/36245852
http://dx.doi.org/10.1002/sdr.1714
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author Rahmandad, Hazhir
author_facet Rahmandad, Hazhir
author_sort Rahmandad, Hazhir
collection PubMed
description How should communities prioritize COVID‐19 vaccinations? Prior studies found that prioritizing the elderly and most vulnerable minimizes deaths. However, prior research has ignored how behavioral responses to risk of disease endogenously change transmission rates. We show that incorporating risk‐driven behavioral responses enhances fit to data and may change prioritization to vaccinating high‐contact individuals. Behavioral responses matter because deaths grow exponentially until communities are compelled to reduce contacts, with deaths stabilizing at levels that oblige higher‐contact groups to sufficiently cut their interactions and slow transmissions. More lives may be saved by vaccinating and taking those high‐contact groups out of transmission chains earlier because the remaining groups will take more precautions while waiting for their turn for vaccination. These findings are especially important considering the need for further vaccination in many countries, the emergence of new variants, and the expected challenge of distributing new vaccines in the coming months and years. © 2022 The Author. System Dynamics Review published by John Wiley & Sons Ltd on behalf of System Dynamics Society.
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spelling pubmed-95378832022-10-11 Behavioral responses to risk promote vaccinating high‐contact individuals first Rahmandad, Hazhir Syst Dyn Rev Fast Track How should communities prioritize COVID‐19 vaccinations? Prior studies found that prioritizing the elderly and most vulnerable minimizes deaths. However, prior research has ignored how behavioral responses to risk of disease endogenously change transmission rates. We show that incorporating risk‐driven behavioral responses enhances fit to data and may change prioritization to vaccinating high‐contact individuals. Behavioral responses matter because deaths grow exponentially until communities are compelled to reduce contacts, with deaths stabilizing at levels that oblige higher‐contact groups to sufficiently cut their interactions and slow transmissions. More lives may be saved by vaccinating and taking those high‐contact groups out of transmission chains earlier because the remaining groups will take more precautions while waiting for their turn for vaccination. These findings are especially important considering the need for further vaccination in many countries, the emergence of new variants, and the expected challenge of distributing new vaccines in the coming months and years. © 2022 The Author. System Dynamics Review published by John Wiley & Sons Ltd on behalf of System Dynamics Society. John Wiley & Sons, Ltd 2022-08-23 2022 /pmc/articles/PMC9537883/ /pubmed/36245852 http://dx.doi.org/10.1002/sdr.1714 Text en © 2022 The Author. System Dynamics Review published by John Wiley & Sons Ltd on behalf of System Dynamics Society. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Fast Track
Rahmandad, Hazhir
Behavioral responses to risk promote vaccinating high‐contact individuals first
title Behavioral responses to risk promote vaccinating high‐contact individuals first
title_full Behavioral responses to risk promote vaccinating high‐contact individuals first
title_fullStr Behavioral responses to risk promote vaccinating high‐contact individuals first
title_full_unstemmed Behavioral responses to risk promote vaccinating high‐contact individuals first
title_short Behavioral responses to risk promote vaccinating high‐contact individuals first
title_sort behavioral responses to risk promote vaccinating high‐contact individuals first
topic Fast Track
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537883/
https://www.ncbi.nlm.nih.gov/pubmed/36245852
http://dx.doi.org/10.1002/sdr.1714
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