Cargando…

Infection control behaviours, intra‐household transmission and quarantine duration: a retrospective cohort analysis of COVID‐19 cases

OBJECTIVES: To study COVID‐19 (Delta Variant) cases and close contacts co‐located within households. Focusing on epidemiology of transmission of COVID‐19, quarantine duration and utilisation of infection control behaviours under a telehealth model of care in an elimination setting. METHODS: A retros...

Descripción completa

Detalles Bibliográficos
Autores principales: McCarthy, Kate L., James, Douglas P., Kumar, Nikhil, Hartel, Gunter, Langley, Matthew, McAuley, Duncan, Bunting, Julie, Rushbrook, Elizabeth, Bennett, Cameron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538556/
https://www.ncbi.nlm.nih.gov/pubmed/35980162
http://dx.doi.org/10.1111/1753-6405.13282
_version_ 1784803365327208448
author McCarthy, Kate L.
James, Douglas P.
Kumar, Nikhil
Hartel, Gunter
Langley, Matthew
McAuley, Duncan
Bunting, Julie
Rushbrook, Elizabeth
Bennett, Cameron
author_facet McCarthy, Kate L.
James, Douglas P.
Kumar, Nikhil
Hartel, Gunter
Langley, Matthew
McAuley, Duncan
Bunting, Julie
Rushbrook, Elizabeth
Bennett, Cameron
author_sort McCarthy, Kate L.
collection PubMed
description OBJECTIVES: To study COVID‐19 (Delta Variant) cases and close contacts co‐located within households. Focusing on epidemiology of transmission of COVID‐19, quarantine duration and utilisation of infection control behaviours under a telehealth model of care in an elimination setting. METHODS: A retrospective cohort analysis examined household spread of infection, duration of quarantine and change in PCR CT value during illness. A survey explored infection control behaviours used by household members during isolation and quarantine. RESULTS: The cohort was 141 individuals in 35 households. Thirty‐seven were index cases, and 48 became positive during quarantine, most within 10 days. Whole‐household infection occurred in 12 households with multiple members. Behaviours focused on fomite transmission reduction rather than preventing aerosol transmission. The median duration of close contact household quarantine was 25 days. The majority of COVID‐19 cases were de‐isolated after 14 days with no evidence of further community transmission. CONCLUSION: Intrahousehold transmission was not universal and, if it occurred, usually occurred quickly. Behaviours utilised focused on fomites, suggesting a need for improved education regarding the potential utilisation of strategies to prevention the transmission of aerosols. Households experienced long durations of home‐based quarantine. IMPLICATIONS FOR PUBLIC HEALTH: The impact of long quarantine durations must be considered, particularly where most community benefit from quarantine is achieved within 10 days from exposure in the setting of the Delta Variant. Education of households regarding aerosol risk reduction is a potential strategy in the household setting of individuals at risk of disease progression.
format Online
Article
Text
id pubmed-9538556
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-95385562022-10-11 Infection control behaviours, intra‐household transmission and quarantine duration: a retrospective cohort analysis of COVID‐19 cases McCarthy, Kate L. James, Douglas P. Kumar, Nikhil Hartel, Gunter Langley, Matthew McAuley, Duncan Bunting, Julie Rushbrook, Elizabeth Bennett, Cameron Aust N Z J Public Health Covid‐19 OBJECTIVES: To study COVID‐19 (Delta Variant) cases and close contacts co‐located within households. Focusing on epidemiology of transmission of COVID‐19, quarantine duration and utilisation of infection control behaviours under a telehealth model of care in an elimination setting. METHODS: A retrospective cohort analysis examined household spread of infection, duration of quarantine and change in PCR CT value during illness. A survey explored infection control behaviours used by household members during isolation and quarantine. RESULTS: The cohort was 141 individuals in 35 households. Thirty‐seven were index cases, and 48 became positive during quarantine, most within 10 days. Whole‐household infection occurred in 12 households with multiple members. Behaviours focused on fomite transmission reduction rather than preventing aerosol transmission. The median duration of close contact household quarantine was 25 days. The majority of COVID‐19 cases were de‐isolated after 14 days with no evidence of further community transmission. CONCLUSION: Intrahousehold transmission was not universal and, if it occurred, usually occurred quickly. Behaviours utilised focused on fomites, suggesting a need for improved education regarding the potential utilisation of strategies to prevention the transmission of aerosols. Households experienced long durations of home‐based quarantine. IMPLICATIONS FOR PUBLIC HEALTH: The impact of long quarantine durations must be considered, particularly where most community benefit from quarantine is achieved within 10 days from exposure in the setting of the Delta Variant. Education of households regarding aerosol risk reduction is a potential strategy in the household setting of individuals at risk of disease progression. Elsevier 2022-12 2023-02-27 /pmc/articles/PMC9538556/ /pubmed/35980162 http://dx.doi.org/10.1111/1753-6405.13282 Text en © 2022 Copyright 2022 THE AUTHORS. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Covid‐19
McCarthy, Kate L.
James, Douglas P.
Kumar, Nikhil
Hartel, Gunter
Langley, Matthew
McAuley, Duncan
Bunting, Julie
Rushbrook, Elizabeth
Bennett, Cameron
Infection control behaviours, intra‐household transmission and quarantine duration: a retrospective cohort analysis of COVID‐19 cases
title Infection control behaviours, intra‐household transmission and quarantine duration: a retrospective cohort analysis of COVID‐19 cases
title_full Infection control behaviours, intra‐household transmission and quarantine duration: a retrospective cohort analysis of COVID‐19 cases
title_fullStr Infection control behaviours, intra‐household transmission and quarantine duration: a retrospective cohort analysis of COVID‐19 cases
title_full_unstemmed Infection control behaviours, intra‐household transmission and quarantine duration: a retrospective cohort analysis of COVID‐19 cases
title_short Infection control behaviours, intra‐household transmission and quarantine duration: a retrospective cohort analysis of COVID‐19 cases
title_sort infection control behaviours, intra‐household transmission and quarantine duration: a retrospective cohort analysis of covid‐19 cases
topic Covid‐19
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538556/
https://www.ncbi.nlm.nih.gov/pubmed/35980162
http://dx.doi.org/10.1111/1753-6405.13282
work_keys_str_mv AT mccarthykatel infectioncontrolbehavioursintrahouseholdtransmissionandquarantinedurationaretrospectivecohortanalysisofcovid19cases
AT jamesdouglasp infectioncontrolbehavioursintrahouseholdtransmissionandquarantinedurationaretrospectivecohortanalysisofcovid19cases
AT kumarnikhil infectioncontrolbehavioursintrahouseholdtransmissionandquarantinedurationaretrospectivecohortanalysisofcovid19cases
AT hartelgunter infectioncontrolbehavioursintrahouseholdtransmissionandquarantinedurationaretrospectivecohortanalysisofcovid19cases
AT langleymatthew infectioncontrolbehavioursintrahouseholdtransmissionandquarantinedurationaretrospectivecohortanalysisofcovid19cases
AT mcauleyduncan infectioncontrolbehavioursintrahouseholdtransmissionandquarantinedurationaretrospectivecohortanalysisofcovid19cases
AT buntingjulie infectioncontrolbehavioursintrahouseholdtransmissionandquarantinedurationaretrospectivecohortanalysisofcovid19cases
AT rushbrookelizabeth infectioncontrolbehavioursintrahouseholdtransmissionandquarantinedurationaretrospectivecohortanalysisofcovid19cases
AT bennettcameron infectioncontrolbehavioursintrahouseholdtransmissionandquarantinedurationaretrospectivecohortanalysisofcovid19cases