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Systematic MRI in persistent post‐Covid‐19 olfactory dysfunction should be reassessed

BACKGROUND: Magnetic resonance imaging (MRI) is the gold standard in the etiological assessment of a persistent olfactory dysfunction (OD). While the utility of imaging in COVID‐19‐related OD has yet to be established, MRI is recommended in all patients with persistent OD. The high prevalence of the...

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Autores principales: Brudasca, Ioana, Lisan, Quentin, Tournegros, Romain, Bensafi, Moustafa, Ferdenzi, Camille, Fournel, Arnaud, Denoix, Luna, Tringali, Stéphane, Fieux, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538635/
https://www.ncbi.nlm.nih.gov/pubmed/36062361
http://dx.doi.org/10.1002/alr.23081
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author Brudasca, Ioana
Lisan, Quentin
Tournegros, Romain
Bensafi, Moustafa
Ferdenzi, Camille
Fournel, Arnaud
Denoix, Luna
Tringali, Stéphane
Fieux, Maxime
author_facet Brudasca, Ioana
Lisan, Quentin
Tournegros, Romain
Bensafi, Moustafa
Ferdenzi, Camille
Fournel, Arnaud
Denoix, Luna
Tringali, Stéphane
Fieux, Maxime
author_sort Brudasca, Ioana
collection PubMed
description BACKGROUND: Magnetic resonance imaging (MRI) is the gold standard in the etiological assessment of a persistent olfactory dysfunction (OD). While the utility of imaging in COVID‐19‐related OD has yet to be established, MRI is recommended in all patients with persistent OD. The high prevalence of the latter after SARS‐CoV‐2 infection means evaluating this strategy is an important public health matter. METHODS: The main objective was to examine the impact of systematic MRI on the management of patients with OD. All adult patients consulting for persistent OD (>2 months) after primary SARS‐COV‐2 infection (PCR) between March 2020 and December 2021 were included (n = 67). The secondary objective was to evaluate the relationship between the severity of the OD as measured by psychophysical testing (ETOC) and the volume of the olfactory bulb (OB) measured by MRI. RESULTS: All patients underwent MRI, and none led to a change in diagnosis or treatment. Among them, 82% (55/67) were considered normal by the radiologist on initial interpretation. There were no significant differences (visual analysis or OB volume) between groups (mild, moderate, and severe hyposmia). CONCLUSION: Systematic MRI may be unnecessary in patients whose persistent OD began soon (a few days) after confirmed SARS‐CoV‐2 infection.
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spelling pubmed-95386352022-10-11 Systematic MRI in persistent post‐Covid‐19 olfactory dysfunction should be reassessed Brudasca, Ioana Lisan, Quentin Tournegros, Romain Bensafi, Moustafa Ferdenzi, Camille Fournel, Arnaud Denoix, Luna Tringali, Stéphane Fieux, Maxime Int Forum Allergy Rhinol Clinical Letter BACKGROUND: Magnetic resonance imaging (MRI) is the gold standard in the etiological assessment of a persistent olfactory dysfunction (OD). While the utility of imaging in COVID‐19‐related OD has yet to be established, MRI is recommended in all patients with persistent OD. The high prevalence of the latter after SARS‐CoV‐2 infection means evaluating this strategy is an important public health matter. METHODS: The main objective was to examine the impact of systematic MRI on the management of patients with OD. All adult patients consulting for persistent OD (>2 months) after primary SARS‐COV‐2 infection (PCR) between March 2020 and December 2021 were included (n = 67). The secondary objective was to evaluate the relationship between the severity of the OD as measured by psychophysical testing (ETOC) and the volume of the olfactory bulb (OB) measured by MRI. RESULTS: All patients underwent MRI, and none led to a change in diagnosis or treatment. Among them, 82% (55/67) were considered normal by the radiologist on initial interpretation. There were no significant differences (visual analysis or OB volume) between groups (mild, moderate, and severe hyposmia). CONCLUSION: Systematic MRI may be unnecessary in patients whose persistent OD began soon (a few days) after confirmed SARS‐CoV‐2 infection. John Wiley and Sons Inc. 2022-09-21 /pmc/articles/PMC9538635/ /pubmed/36062361 http://dx.doi.org/10.1002/alr.23081 Text en © 2022 The Authors. International Forum of Allergy & Rhinology published by Wiley Periodicals LLC on behalf of American Academy of Otolaryngic Allergy and American Rhinologic Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Letter
Brudasca, Ioana
Lisan, Quentin
Tournegros, Romain
Bensafi, Moustafa
Ferdenzi, Camille
Fournel, Arnaud
Denoix, Luna
Tringali, Stéphane
Fieux, Maxime
Systematic MRI in persistent post‐Covid‐19 olfactory dysfunction should be reassessed
title Systematic MRI in persistent post‐Covid‐19 olfactory dysfunction should be reassessed
title_full Systematic MRI in persistent post‐Covid‐19 olfactory dysfunction should be reassessed
title_fullStr Systematic MRI in persistent post‐Covid‐19 olfactory dysfunction should be reassessed
title_full_unstemmed Systematic MRI in persistent post‐Covid‐19 olfactory dysfunction should be reassessed
title_short Systematic MRI in persistent post‐Covid‐19 olfactory dysfunction should be reassessed
title_sort systematic mri in persistent post‐covid‐19 olfactory dysfunction should be reassessed
topic Clinical Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538635/
https://www.ncbi.nlm.nih.gov/pubmed/36062361
http://dx.doi.org/10.1002/alr.23081
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