Comparative assessment of viral dynamic models for SARS‐CoV‐2 for pharmacodynamic assessment in early treatment trials

Pharmacometric analyses of time series viral load data may detect drug effects with greater power than approaches using single time points. Because SARS‐CoV‐2 viral load rapidly rises and then falls, viral dynamic models have been used. We compared different modelling approaches when analysing Phase...

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Detalles Bibliográficos
Autores principales: Agyeman, Akosua A., You, Tao, Chan, Phylinda L. S., Lonsdale, Dagan O., Hadjichrysanthou, Christoforos, Mahungu, Tabitha, Wey, Emmanuel Q., Lowe, David M., Lipman, Marc C. I., Breuer, Judy, Kloprogge, Frank, Standing, Joseph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538685/
https://www.ncbi.nlm.nih.gov/pubmed/36040430
http://dx.doi.org/10.1111/bcp.15518

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