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Type I interferon signaling deficiency results in dysregulated innate immune responses to SARS‐CoV‐2 in mice

SARS‐CoV‐2 is a newly emerged coronavirus, causing the global pandemic of respiratory coronavirus disease (COVID‐19). The type I interferon (IFN) pathway is of particular importance for anti‐viral defence and recent studies identified that type I IFNs drive early inflammatory responses to SARS‐CoV‐2...

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Detalles Bibliográficos
Autores principales: Ogger, Patricia P., Martín, Minerva Garcia, Michalaki, Christina, Zhou, Jie, Brown, Jonathan C., Du, Yue, Miah, Kamran M., Habib, Omar, Hyde, Stephen C., Gill, Deborah R., Barclay, Wendy S., Johansson, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538859/
https://www.ncbi.nlm.nih.gov/pubmed/36106692
http://dx.doi.org/10.1002/eji.202249913