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Case Report: Successful therapy with all-trans retinoic acid combined with chemotherapy followed by hematopoietic stem cell transplantation for acute promyelocytic leukemia carrying the BCOR-RARA fusion gene
Acute promyelocytic leukemia (APL) is characterized by the balanced translocation of chromosomes 15 and 17, resulting in the formation of PML-RARA fusion gene. More than 98% of APL have PML-RARA fusion, and less than 2% have other types of RARA gene partners, which named variant APL (vAPL). In the p...
Autores principales: | Chen, Li, Zhu, Hongming, Zhu, Yongmei, Jin, Wen, Dong, Fangyi, Li, Jianfeng, Hu, Jiong, Chen, Qiusheng, Wang, Kankan, Li, Junmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539026/ https://www.ncbi.nlm.nih.gov/pubmed/36212492 http://dx.doi.org/10.3389/fonc.2022.1013046 |
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