Altered distribution and function of NK-cell subsets lead to impaired tumor surveillance in JAK2V617F myeloproliferative neoplasms

In cancer, tumor cells and their neoplastic microenvironment can sculpt the immunogenic phenotype of a developing tumor. In this context, natural killer (NK) cells are subtypes of lymphocytes of the innate immune system recognized for their potential to eliminate neoplastic cells, not only through d...

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Detalles Bibliográficos
Autores principales: Fernandes de Oliveira Costa, Amanda, Olops Marani, Leticia, Mantello Bianco, Thiago, Queiroz Arantes, Adriana, Aparecida Lopes, Izabela, Antonio Pereira-Martins, Diego, Carvalho Palma, Leonardo, Santos Scheucher, Priscila, Lilian dos Santos Schiavinato, Josiane, Sarri Binelli, Larissa, Araújo Silva, Cleide, Kobayashi, Susumu S., Agostinho Machado-Neto, João, Magalhães Rego, Eduardo, Samuel Welner, Robert, Lobo de Figueiredo-Pontes, Lorena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539129/
https://www.ncbi.nlm.nih.gov/pubmed/36211444
http://dx.doi.org/10.3389/fimmu.2022.768592

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