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Prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice
BACKGROUND: Left ventricular longitudinal strain is an emerging marker of ventricular systolic function. However, the prognostic value of apical four-chamber longitudinal strain after heart valve surgery in real-world clinical practice is uncertain. The authors investigated whether left ventricular...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Anesthesiologists
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539422/ https://www.ncbi.nlm.nih.gov/pubmed/35700980 http://dx.doi.org/10.4097/kja.22201 |
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author | Nam, Jae-Sik Chin, Ji-Hyun Kang, Hyun-Uk Kim, Juyoun Joung, Kyoung-Woon Choi, In-Cheol |
author_facet | Nam, Jae-Sik Chin, Ji-Hyun Kang, Hyun-Uk Kim, Juyoun Joung, Kyoung-Woon Choi, In-Cheol |
author_sort | Nam, Jae-Sik |
collection | PubMed |
description | BACKGROUND: Left ventricular longitudinal strain is an emerging marker of ventricular systolic function. However, the prognostic value of apical four-chamber longitudinal strain after heart valve surgery in real-world clinical practice is uncertain. The authors investigated whether left ventricular apical four-chamber longitudinal strain measured in real-world practice is helpful for predicting postoperative outcomes in patients undergoing heart valve surgery. METHODS: This observational cohort study was conducted in patients who underwent heart valve surgery between January 2014 and December 2018 at a tertiary hospital in South Korea. The exposure of interest was preoperative left ventricular apical four-chamber longitudinal strain. The primary outcome was postoperative all-cause mortality. RESULTS: Among 1,773 study patients (median age, 63 years; female, 45.9%), 132 (7.4%) died during a median follow-up of 27.2 months. Preoperative left ventricular apical four-chamber longitudinal strain was significantly associated with all-cause mortality (adjusted hazard ratio, 0.94 per 1% increment in absolute value; 95% CI [0.90, 0.99], P = 0.022), whereas left ventricular ejection fraction (LVEF) was not significantly associated with all-cause mortality (adjusted hazard ratio: 1.01, 95% CI [0.99, 1.03], P = 0.222). Moreover, combining left ventricular apical four-chamber longitudinal strain to the LVEF and conventional prognostic factors enhance the prognostic model for all-cause mortality (P = 0.022). CONCLUSIONS: In patients undergoing heart valve surgery without coronary artery disease, left ventricular apical four-chamber longitudinal strain measured in real-world clinical practice was independently associated with postoperative survival. Left ventricular longitudinal strain measurement may be helpful for outcome prediction after valve surgery. |
format | Online Article Text |
id | pubmed-9539422 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Korean Society of Anesthesiologists |
record_format | MEDLINE/PubMed |
spelling | pubmed-95394222022-10-17 Prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice Nam, Jae-Sik Chin, Ji-Hyun Kang, Hyun-Uk Kim, Juyoun Joung, Kyoung-Woon Choi, In-Cheol Korean J Anesthesiol Clinical Research Article BACKGROUND: Left ventricular longitudinal strain is an emerging marker of ventricular systolic function. However, the prognostic value of apical four-chamber longitudinal strain after heart valve surgery in real-world clinical practice is uncertain. The authors investigated whether left ventricular apical four-chamber longitudinal strain measured in real-world practice is helpful for predicting postoperative outcomes in patients undergoing heart valve surgery. METHODS: This observational cohort study was conducted in patients who underwent heart valve surgery between January 2014 and December 2018 at a tertiary hospital in South Korea. The exposure of interest was preoperative left ventricular apical four-chamber longitudinal strain. The primary outcome was postoperative all-cause mortality. RESULTS: Among 1,773 study patients (median age, 63 years; female, 45.9%), 132 (7.4%) died during a median follow-up of 27.2 months. Preoperative left ventricular apical four-chamber longitudinal strain was significantly associated with all-cause mortality (adjusted hazard ratio, 0.94 per 1% increment in absolute value; 95% CI [0.90, 0.99], P = 0.022), whereas left ventricular ejection fraction (LVEF) was not significantly associated with all-cause mortality (adjusted hazard ratio: 1.01, 95% CI [0.99, 1.03], P = 0.222). Moreover, combining left ventricular apical four-chamber longitudinal strain to the LVEF and conventional prognostic factors enhance the prognostic model for all-cause mortality (P = 0.022). CONCLUSIONS: In patients undergoing heart valve surgery without coronary artery disease, left ventricular apical four-chamber longitudinal strain measured in real-world clinical practice was independently associated with postoperative survival. Left ventricular longitudinal strain measurement may be helpful for outcome prediction after valve surgery. Korean Society of Anesthesiologists 2022-10 2022-06-15 /pmc/articles/PMC9539422/ /pubmed/35700980 http://dx.doi.org/10.4097/kja.22201 Text en Copyright © The Korean Society of Anesthesiologists, 2022 https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Research Article Nam, Jae-Sik Chin, Ji-Hyun Kang, Hyun-Uk Kim, Juyoun Joung, Kyoung-Woon Choi, In-Cheol Prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice |
title | Prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice |
title_full | Prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice |
title_fullStr | Prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice |
title_full_unstemmed | Prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice |
title_short | Prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice |
title_sort | prognostic value of left ventricular apical four-chamber longitudinal strain after heart valve surgery in real-world practice |
topic | Clinical Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539422/ https://www.ncbi.nlm.nih.gov/pubmed/35700980 http://dx.doi.org/10.4097/kja.22201 |
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