Identification of amino acid domains of Borrelia burgdorferi P66 that are surface exposed and important for localization, oligomerization, and porin function of the protein

P66, a bifunctional integral outer membrane protein, is necessary for Borrelia burgdorferi to establish initial infection and to disseminate in mice. The integrin binding function of P66 facilitates extravasation and dissemination, but the role of its porin function during murine infection has not b...

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Detalles Bibliográficos
Autores principales: Curtis, Michael W., Fierros, Christa H., Hahn, Beth L., Surdel, Matthew C., Kessler, Julie, Anderson, Phillip N., Vandewalle-Capo, Marine, Bonde, Mari, Zhu, Jieqing, Bergström, Sven, Coburn, Jenifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539438/
https://www.ncbi.nlm.nih.gov/pubmed/36211976
http://dx.doi.org/10.3389/fcimb.2022.991689

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