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Mutations within the selectivity filter reveal that Kv1 channels have distinct propensities to slow inactivate

Voltage-activated potassium (Kv) channels open in response to membrane depolarization and subsequently inactivate through distinct mechanisms. For the model Shaker Kv channel from Drosophila, fast N-type inactivation is thought to occur by a mechanism involving blockade of the internal pore by the N...

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Detalles Bibliográficos
Autores principales: Wu, Xiaosa, Gupta, Kanchan, Swartz, Kenton J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539455/
https://www.ncbi.nlm.nih.gov/pubmed/36197416
http://dx.doi.org/10.1085/jgp.202213222