Cargando…
Mutations within the selectivity filter reveal that Kv1 channels have distinct propensities to slow inactivate
Voltage-activated potassium (Kv) channels open in response to membrane depolarization and subsequently inactivate through distinct mechanisms. For the model Shaker Kv channel from Drosophila, fast N-type inactivation is thought to occur by a mechanism involving blockade of the internal pore by the N...
Autores principales: | Wu, Xiaosa, Gupta, Kanchan, Swartz, Kenton J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539455/ https://www.ncbi.nlm.nih.gov/pubmed/36197416 http://dx.doi.org/10.1085/jgp.202213222 |
Ejemplares similares
-
Structure of the Shaker Kv channel and mechanism of slow C-type inactivation
por: Tan, Xiao-Feng, et al.
Publicado: (2022) -
Kv1 channel inactivation: Slow and slower
por: Short, Ben
Publicado: (2022) -
Inactivation of the Kv2.1 channel through electromechanical coupling
por: Fernández-Mariño, Ana I., et al.
Publicado: (2023) -
Constitutive Activation of the Shaker Kv Channel
por: Sukhareva, Manana, et al.
Publicado: (2003) -
Exploring structure-function relationships between TRP and Kv channels
por: Kalia, Jeet, et al.
Publicado: (2013)