Cargando…

Class 3 phosphoinositide 3‐kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity

AIM: Lipid kinase class 3 phosphoinositide 3‐kinase (PI3K) and nuclear receptor transcription factor glucocorticoid receptor (GR) play essential physiological roles in metabolic adaptation to fasting by activating lysosomal degradation by autophagy and metabolic gene expression, yet their functional...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shibayama, Yui, Alkhoury, Chantal, Nemazanyy, Ivan, F Henneman, Nathaniel, Cagnard, Nicolas, Girard, Muriel, Atsumi, Tatsuya, Panasyuk, Ganna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Signalling
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539506/ https://www.ncbi.nlm.nih.gov/pubmed/35094500 http://dx.doi.org/10.1111/apha.13793

Ejemplares similares

The class 3 PI3K coordinates autophagy and mitochondrial lipid catabolism by controlling nuclear receptor PPARα
por: Iershov, Anton, et al.
Publicado: (2019)

Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis
por: Alkhoury, Chantal, et al.
Publicado: (2023)

Class II Phosphoinositide 3-Kinase Regulates Exocytosis of Insulin Granules in Pancreatic β Cells
por: Dominguez, Veronica, et al.
Publicado: (2011)

PAQR3 Modulates Insulin Signaling by Shunting Phosphoinositide 3-Kinase p110α to the Golgi Apparatus
por: Wang, Xiao, et al.
Publicado: (2013)

The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P(3)) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin α(IIb)β(3) Outside-in Signaling
por: Battram, Anthony M., et al.
Publicado: (2017)

Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and K(Ca)3.1 ion channels, but involves phosphoinositide 3-kinase
por: Cortés Franco, Klaus-Daniel, et al.
Publicado: (2022)

Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling
por: Nemazanyy, Ivan, et al.
Publicado: (2015)

Paradigms of receptor kinase signaling in plants
por: Bender, Kyle W., et al.
Publicado: (2023)

Class (I) Phosphoinositide 3-Kinases in the Tumor Microenvironment
por: Gyori, David, et al.
Publicado: (2017)

Nuts and bolts of the salt-inducible kinases (SIKs)
por: Darling, Nicola J., et al.
Publicado: (2021)

Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis
por: Kuo, Taiyi, et al.
Publicado: (2017)

Gal-3 is a potential biomarker for spinal cord injury and Gal-3 deficiency attenuates neuroinflammation through ROS/TXNIP/NLRP3 signaling pathway
por: Ren, Zhouliang, et al.
Publicado: (2019)

IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold
por: Dixon, Miles J., et al.
Publicado: (2012)

Protein kinase C showcases allosteric control: activation of LRRK1
por: Tovell, Hannah, et al.
Publicado: (2023)

Redox-dependent dimerization of p38α mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3
por: Bassi, Rekha, et al.
Publicado: (2017)

Depletion of plasma membrane–associated phosphoinositides mimics inhibition of TRPM7 channels by cytosolic Mg(2+), spermine, and pH
por: Zhelay, Tetyana, et al.
Publicado: (2018)

Phosphatidylserine binding directly regulates TIM-3 function
por: Smith, Courtney M., et al.
Publicado: (2021)

AMP-activated protein kinase — a journey from 1 to 100 downstream targets
por: Hardie, D. Grahame
Publicado: (2022)

Functions and regulation of the serine/threonine protein kinase CK1 family: moving beyond promiscuity
por: Fulcher, Luke J., et al.
Publicado: (2020)

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding
por: Kalogeropulou, Alexia F., et al.
Publicado: (2022)

Insulin Growth Factor-2 Binding Protein 3 (IGF2BP3) Is a Glioblastoma-specific Marker That Activates Phosphatidylinositol 3-Kinase/Mitogen-activated Protein Kinase (PI3K/MAPK) Pathways by Modulating IGF-2
por: Suvasini, Ramaswamy, et al.
Publicado: (2011)

Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3
por: Kokoszka, Malgorzata E., et al.
Publicado: (2018)

Dual Regulation of Glycogen Synthase Kinase 3 (GSK3)α/β by Protein Kinase C (PKC)α and Akt Promotes Thrombin-mediated Integrin α(IIb)β(3) Activation and Granule Secretion in Platelets
por: Moore, Samantha F., et al.
Publicado: (2013)

Trafficking regulator of GLUT4-1 (TRARG1) is a GSK3 substrate
por: Duan, Xiaowen, et al.
Publicado: (2022)

Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis
por: Tibolla, Gianpaolo, et al.
Publicado: (2013)

Janus kinase 3 regulates adherens junctions and epithelial mesenchymal transition through β-catenin
por: Mishra, Jayshree, et al.
Publicado: (2017)

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC
por: Snelling, Tom, et al.
Publicado: (2022)

Selective inhibition of intestinal guanosine 3′,5′-cyclic monophosphate signaling by small-molecule protein kinase inhibitors
por: Bijvelds, Marcel J. C., et al.
Publicado: (2018)

Class I and class III phosphoinositide 3-kinases are required for actin polymerization that propels phagosomes
por: Bohdanowicz, Michal, et al.
Publicado: (2010)

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)
por: Huang, Xueqin, et al.
Publicado: (2023)

Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1ϵ and Frizzled5
por: Bernatík, Ondřej, et al.
Publicado: (2014)

Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15
por: Hayes, Sebastian D., et al.
Publicado: (2012)

Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with Type 2 diabetes with and without fatty liver
por: Macfarlane, D. P., et al.
Publicado: (2014)

A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules
por: Panasyuk, Ganna, et al.
Publicado: (2008)

Phosphorylation of the Kinase Interaction Motif in Mitogen-activated Protein (MAP) Kinase Phosphatase-4 Mediates Cross-talk between Protein Kinase A and MAP Kinase Signaling Pathways
por: Dickinson, Robin J., et al.
Publicado: (2011)

Signaling to Extracellular Signal-regulated Kinase from ErbB1 Kinase and Protein Kinase C: FEEDBACK, HETEROGENEITY, AND GATING
por: Perrett, Rebecca M, et al.
Publicado: (2013)

Loss of Class III Phosphoinositide 3-Kinase Vps34 Results in Cone Degeneration
por: Rajala, Ammaji, et al.
Publicado: (2020)

Phosphoinositide‐dependent Kinase‐1 (PDPK1) regulates serum/glucocorticoid‐regulated Kinase 3 (SGK3) for prostate cancer cell survival
por: Nalairndran, Geetha, et al.
Publicado: (2020)

Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor
por: MacLachlan, Bruce J., et al.
Publicado: (2020)

Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration
por: Maffucci, Tania, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_medrs46tth4kcif0mn9e54enss