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Sirtuin1 meditated modification of Notch1 intracellular domain regulates nucleolar localization and activation of distinct signaling cascades

Notch signaling is involved in cell fate decisions in the development and maintenance of tissue homeostasis. Spatial regulation of the Notch1 intracellular domain (NIC1), has been shown to underpin signaling outcomes mediated by this receptor. We recently reported a putative Nucleolar Localization S...

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Detalles Bibliográficos
Autores principales: Saini, Neetu, Bheeshmachar, Geetha, Sarin, Apurva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539544/
https://www.ncbi.nlm.nih.gov/pubmed/36211456
http://dx.doi.org/10.3389/fcell.2022.988816