Corticotroph isolation from Pomc‐eGFP mice reveals sustained transcriptional dysregulation characterising a mouse model of glucocorticoid‐induced suppression of the hypothalamus–pituitary–adrenal axis

Glucocorticoids (GC) are prescribed for periods > 3 months to 1%–3% of the UK population; 10%–50% of these patients develop hypothalamus‐pituitary–adrenal (HPA) axis suppression, which may last over 6 months and is associated with morbidity and mortality. Recovery of the pituitary and hypothalamu...

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Detalles Bibliográficos
Autores principales: Duncan, Peter J., McClafferty, Heather, Nolan, Oscar, Ding, Qinghui, Homer, Natalie Z. M., Le Tissier, Paul, Walker, Brian R., Shipston, Michael J., Romanò, Nicola, Chambers, Thomas J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Fundamental and Mechanistic Neuroendocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539609/
https://www.ncbi.nlm.nih.gov/pubmed/35833423
http://dx.doi.org/10.1111/jne.13165

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