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The exploration of the potential mechanism of oxymatrine-mediated antipruritic effect based on network pharmacology and weighted gene co-expression network analysis

The treatment of chronic itch is considered to be a challenge for its non-histamine dependence and the search for alternative medicine is still striving. The pathology of the chronic itch is closely related to immune system regulation and inflammatory response. Oxymatrine (OMT) is a traditional Chin...

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Detalles Bibliográficos
Autores principales: Luo, Zhenhui, Zhao, Tingting, Yi, Mengqin, Wang, Tingting, Zhang, Zhenglang, Li, Wenbin, Lin, Na, Liang, Shangdong, Verkhratsky, Alexei, Nie, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539766/
https://www.ncbi.nlm.nih.gov/pubmed/36210824
http://dx.doi.org/10.3389/fphar.2022.946602