GPR125 (ADGRA3) is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral membrane and regulates epithelial apicobasal polarity

The adhesion family of G protein–coupled receptors (GPCRs) is defined by an N-terminal large extracellular region that contains various adhesion-related domains and a highly-conserved GPCR-autoproteolysis-inducing (GAIN) domain, the latter of which is located immediately before a canonical seven-tra...

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Detalles Bibliográficos
Autores principales: Sakurai, Tsubasa, Kamakura, Sachiko, Hayase, Junya, Kohda, Akira, Nakamura, Masafumi, Sumimoto, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539791/
https://www.ncbi.nlm.nih.gov/pubmed/36089063
http://dx.doi.org/10.1016/j.jbc.2022.102475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539791/
https://www.ncbi.nlm.nih.gov/pubmed/36089063
http://dx.doi.org/10.1016/j.jbc.2022.102475

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