Triptolide in the treatment of systemic lupus erythematosus - regulatory effects on miR-146a in B cell TLR7 signaling pathway in mice

Objective: To clarify the mechanism of triptolide (TP) in alleviating the conditions underlying SLE. Methods: Eight-week-old MRL/lpr mice were randomly divided into a model group (n = 5), low-dose TP (TP-L) group (n = 5), and high-dose TP (TP-H) group (n = 5). Mice in these groups were gavaged with...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Zhang, FengQi, Gao, YiNi, Wang, MeiJiao, Gao, Yan, Li, HaiChang, Sun, Jing, Wen, ChengPing, Xie, ZhiJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539794/
https://www.ncbi.nlm.nih.gov/pubmed/36210830
http://dx.doi.org/10.3389/fphar.2022.952775

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