A novel germline HAVCR2 (TIM-3) compound heterozygous mutation is related to hemophagocytic lymphohistiocytic syndrome in EBV-positive peripheral T-cell lymphoma (NOS) with down-regulated TIM-3 signaling

Recently, it have been reported that Hepatitis A Virus-Cellular Receptor 2(HAVCR2,encoding T-cell immunoglobulin and Mucin-Containing Protein 3[TIM3]) mutations are associated with severe hemophagocytic syndrome(HLH) in subcutaneous panniculitis-like T-cell lymphoma(SPTCL),and there are also frequen...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Wang, Zhihua, Hu, Guoyu, Li, Jieping, Chen, Yongheng, Jiang, Yi, Zhong, Haiying, Liu, Xianling, Hu, Chunhong, Peng, Honglin, Xu, Yunxiao, Cheng, Zhao, Zhang, Guangsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539911/
https://www.ncbi.nlm.nih.gov/pubmed/36212426
http://dx.doi.org/10.3389/fonc.2022.870676

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