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External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development

Despite external environmental changes in walking, such as manipulating gait speed, previous studies have shown that the underlying muscle synergy structures (synergy weights or vectors) rarely vary. The purpose of this study is to examine if external environmental changes to the walking task influe...

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Autores principales: Kim, Yushin, Bulea, Thomas C., Damiano, Diane L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540389/
https://www.ncbi.nlm.nih.gov/pubmed/36211124
http://dx.doi.org/10.3389/fnhum.2022.976100
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author Kim, Yushin
Bulea, Thomas C.
Damiano, Diane L.
author_facet Kim, Yushin
Bulea, Thomas C.
Damiano, Diane L.
author_sort Kim, Yushin
collection PubMed
description Despite external environmental changes in walking, such as manipulating gait speed, previous studies have shown that the underlying muscle synergy structures (synergy weights or vectors) rarely vary. The purpose of this study is to examine if external environmental changes to the walking task influence muscle synergies in children with cerebral palsy (CP) and/or typical development (TD). To identify muscle synergies, we extracted muscle synergies from eight children with CP and eight age-matched TD in three treadmill walking conditions, e.g., baseline (adjusted to individual comfortable walking speed), variable speed (VS), or restricted foot width (RW). Then, we grouped similar muscle synergies using k-mean clustering and discriminant analyses from all datasets of individual synergy structures. Proportion tests exhibited six clusters of muscle synergies predominantly arising from children with CP and four clusters from children with TD. Also, the proportion of muscle synergies was significantly different in four of the CP-preferred clusters across conditions. Specifically, the proportion of the baseline condition was significantly different from VS and RW conditions in one and two clusters, respectively. The proportion was significantly different between VS and RW conditions in four clusters. Cadence and step lengths differed across conditions but not groups which makes the group differences in proportion even more notable. In contrast, step width, while significantly lower in CP, did not differ across conditions. Our findings demonstrate that muscle synergies in children with CP are more sensitive to changes in the external walking environment than in typically developing children.
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spelling pubmed-95403892022-10-08 External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development Kim, Yushin Bulea, Thomas C. Damiano, Diane L. Front Hum Neurosci Neuroscience Despite external environmental changes in walking, such as manipulating gait speed, previous studies have shown that the underlying muscle synergy structures (synergy weights or vectors) rarely vary. The purpose of this study is to examine if external environmental changes to the walking task influence muscle synergies in children with cerebral palsy (CP) and/or typical development (TD). To identify muscle synergies, we extracted muscle synergies from eight children with CP and eight age-matched TD in three treadmill walking conditions, e.g., baseline (adjusted to individual comfortable walking speed), variable speed (VS), or restricted foot width (RW). Then, we grouped similar muscle synergies using k-mean clustering and discriminant analyses from all datasets of individual synergy structures. Proportion tests exhibited six clusters of muscle synergies predominantly arising from children with CP and four clusters from children with TD. Also, the proportion of muscle synergies was significantly different in four of the CP-preferred clusters across conditions. Specifically, the proportion of the baseline condition was significantly different from VS and RW conditions in one and two clusters, respectively. The proportion was significantly different between VS and RW conditions in four clusters. Cadence and step lengths differed across conditions but not groups which makes the group differences in proportion even more notable. In contrast, step width, while significantly lower in CP, did not differ across conditions. Our findings demonstrate that muscle synergies in children with CP are more sensitive to changes in the external walking environment than in typically developing children. Frontiers Media S.A. 2022-09-23 /pmc/articles/PMC9540389/ /pubmed/36211124 http://dx.doi.org/10.3389/fnhum.2022.976100 Text en Copyright © 2022 Kim, Bulea and Damiano. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Kim, Yushin
Bulea, Thomas C.
Damiano, Diane L.
External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development
title External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development
title_full External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development
title_fullStr External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development
title_full_unstemmed External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development
title_short External walking environment differentially affects muscle synergies in children with cerebral palsy and typical development
title_sort external walking environment differentially affects muscle synergies in children with cerebral palsy and typical development
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540389/
https://www.ncbi.nlm.nih.gov/pubmed/36211124
http://dx.doi.org/10.3389/fnhum.2022.976100
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