Genomewide Association Study of Simvastatin Pharmacokinetics

We investigated genetic determinants of single‐dose simvastatin pharmacokinetics in a prospective study of 170 subjects and a retrospective cohort of 59 healthy volunteers. In a microarray‐based genomewide association study with the prospective data, the SLCO1B1 c.521T>C (p.Val174Ala, rs4149056)...

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Detalles Bibliográficos
Autores principales: Mykkänen, Anssi J. H., Taskinen, Suvi, Neuvonen, Mikko, Paile‐Hyvärinen, Maria, Tarkiainen, E. Katriina, Lilius, Tuomas, Tapaninen, Tuija, Backman, Janne T., Tornio, Aleksi, Niemi, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540481/
https://www.ncbi.nlm.nih.gov/pubmed/35652242
http://dx.doi.org/10.1002/cpt.2674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9540481/
https://www.ncbi.nlm.nih.gov/pubmed/35652242
http://dx.doi.org/10.1002/cpt.2674

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